Effect of LexA on Chromosomal Integration of CTXϕ in Vibrio cholerae

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Effect of LexA on Chromosomal Integration of CTXϕ in Vibrio cholerae.

UNLABELLED The genesis of toxigenic Vibrio cholerae involves acquisition of CTXϕ, a single-stranded DNA (ssDNA) filamentous phage that encodes cholera toxin (CT). The phage exploits host-encoded tyrosine recombinases (XerC and XerD) for chromosomal integration and lysogenic conversion. The replicative genome of CTXϕ produces ssDNA by rolling-circle replication, which may be used either for viri...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 2016

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.00674-15